Aneuploidy and Isochromosome Formation in Drug-Resistant Candida albicans
نویسندگان
چکیده
منابع مشابه
Aneuploidy and isochromosome formation in drug-resistant Candida albicans.
Resistance to the limited number of available antifungal drugs is a serious problem in the treatment of Candida albicans. We found that aneuploidy in general and a specific segmental aneuploidy, consisting of an isochromosome composed of the two left arms of chromosome 5, were associated with azole resistance. The isochromosome forms around a single centromere flanked by an inverted repeat and ...
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ژورنال
عنوان ژورنال: Science
سال: 2006
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1128242